Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.

Rescued from the guillotine by his devoted dwarf Fritz, the Baron relocates to Carlsbruck, where he continues his gruesome experiments.

Once hounded from his castle by outraged villagers for creating a monstrous living being, Baron Frankenstein returns to Karlstaad. High in the mountains they stumble on the body of the creature, perfectly preserved in the ice. He is brought back to life with the help of the hypnotist Zoltan who now controls the creature. Can Frankenstein break Zoltan's hypnotic spell that incites the monster to commit these horrific murders or will Zoltan induce the creature to destroy its creator?

A deformed tormented girl drowns herself after her lover is framed for murder and guillotined. Baron Frankenstein, experimenting with the transfer of souls, places the boy's soul into her body, bringing Christina back to life. Driven by revenge, she carries out a violent retribution on those responsible for both deaths.

Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.

Young Victor Frankenstein, a cold, arrogant and womanizing genius, is angry when his father Alphonse forbids him to continue his anatomy experiments. He ruthlessly murders Alphonse by sabotaging his shotgun, consequently inheriting the title of Baron von Frankenstein and the family fortune. He uses the money to enter medical school in Vienna, but is forced to return home following an affair with the daughter of the schools Dean. Returning to his own castle, Victor sets up a laboratory and starts a series of experiments involving the revival of the dead. He eventually builds a composite body from human parts, which he then brings to life. The creature goes on a homicidal rampage until it is accidentally destroyed when a little girl accidentally causes the vat in which it has been hidden to be flooded with acid, leaving behind only the creature's shoes floating on the surface.

Dr Simon Helder, sentenced to an insane asylum for crimes against humanity, recognises its director as the brilliant Baron Frankenstein, the man whose work he had been trying to emulate before his imprisonment. Frankenstein utilises Helder's medical knowledge for a project he has been working on for some time. He is assembling a man from vital organs extracted from various inmates in the asylum. And the Baron will resort to murder to acquire the perfect specimens for his most ambitious project ever.